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Ptf1atm1(cre)Hnak
Targeted Allele Detail
Summary
Symbol: Ptf1atm1(cre)Hnak
Name: pancreas specific transcription factor, 1a; targeted mutation 1, Hassan Nakhai
MGI ID: MGI:3701996
Synonyms: p48-cre, Ptf1a-cre(ex1), Ptf1aCre(ex1), Ptf1atm1(cre)Nak
Gene: Ptf1a  Location: Chr2:19450474-19452312 bp, + strand  Genetic Position: Chr2, 13.37 cM, cytoband A2
Alliance: Ptf1atm1(cre)Hnak page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:119184
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Ptf1atm1(cre)Hnak expression driven by 1 gene
 
Mutation details: Cre recombinase replaced part of exon 1. A neomycin resistance gene included in the vector was subsequently removed via transient FLP expression. (J:119184)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Ptf1a (mouse)
Summary of all recombinase alleles driven by Ptf1a.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 4 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ptf1a Mutation:  31 strains or lines available
References
Original:  J:119184 Nakhai H, et al., Ptf1a is essential for the differentiation of GABAergic and glycinergic amacrine cells and horizontal cells in the mouse retina. Development. 2007 Mar;134(6):1151-60
All:  61 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory