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Tg(Thy1-cre)703Vaw
Transgene Detail
Summary
Symbol: Tg(Thy1-cre)703Vaw
Name: transgene insertion 703, Valerie A Wallace
MGI ID: MGI:3702324
Synonyms: Tg(Thy1-cre)729Vaw, Thy1-Cre
Transgene: Tg(Thy1-cre)703Vaw  Location: unknown  
Alliance: Tg(Thy1-cre)703Vaw page
Transgene
origin
Strain of Origin:  C57BL/6 x C3H
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Thy1-cre)703Vaw expression driven by 1 gene
 
Mutation detailsA 1.1kb Cre-containing cDNA fragment was fused to the Thy promoter from the Thy-1.2 expression cassette. Crosses to Z/AP or ROSA reporter mice and subsequent beta-galactosidase staining assays were used to tested transgene insertion. Twelve independent lines derived from eleven founder mice exhibit variable expression in retinal neuroblast layer, retinal ganglion cell layer, cortex neuroblast layer and cortex postmitotic cells, cerebellum external ganglion layer, cerebellum Purkinje cell layer, cerebellum granule cell layer, the choroid plexus, spinal cord and dorsal root ganglia. This record describes line 729 and is a representative record for all lines. (J:77070)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Thy1 (species not specified)
Summary of all recombinase alleles driven by Thy1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:77070 Campsall KD, et al., Characterization of transgene expression and Cre recombinase activity in a panel of Thy-1 promoter-Cre transgenic mice. Dev Dyn. 2002 Jun;224(2):135-43
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory