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Gene Expression Data
Assay Details
Assay
Reference: J:119915 Haworth K, et al., Expression of the Scube3 epidermal growth factor-related gene during early embryonic development in the mouse. Gene Expr Patterns. 2007 Apr;7(5):630-634
Assay type: RNA in situ
MGI Accession ID: MGI:3709607
Gene symbol: Scube3
Gene name: signal peptide, CUB domain, EGF-like 3
Probe: MGC clone 105171
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 2A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future brain Strong Regionally restricted 2A Expression is ventral.
TS15: neural tube Strong Regionally restricted 2A Expression is ventral.
TS15: branchial arch ectoderm Strong 2A
TS15: branchial arch endoderm Strong 2A
TS15: limb Strong 2A
TS15: head mesenchyme derived from neural crest Present Regionally restricted 2A Expression is in the craniofacial region.
TS15: limb ectoderm Present 2A
TS15: limb mesenchyme Present 2A

Specimen 2B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future brain Strong Regionally restricted 2B Expression is ventral.
TS15: neural tube Strong Regionally restricted 2B Expression is ventral.
TS15: branchial arch ectoderm Strong 2B
TS15: branchial arch endoderm Strong 2B
TS15: limb Strong 2B
TS15: limb ectoderm Present 2B
TS15: limb mesenchyme Present 2B

Specimen 2C: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future brain Strong Regionally restricted 2C Expression is ventral.
TS15: neural tube Strong Regionally restricted 2C Expression is ventral.
TS15: branchial arch ectoderm Strong 2C
TS15: branchial arch endoderm Strong 2C
TS15: limb Strong 2C
TS15: otocyst Strong Regionally restricted 2C Expression is in the lateral regions.
TS15: limb ectoderm Present 2C
TS15: limb mesenchyme Present 2C

Specimen 2D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: branchial arch ectoderm Strong Regionally restricted 2D Expression is in caudal regions.
TS17: limb ectoderm Present 2D
TS17: limb mesenchyme Present 2D
TS17: lung Present 2D
TS17: stomach Present Regionally restricted 2D Expression is in the foregut endoderm of the future stomach.
TS17: brain Present Regionally restricted 2D Expression is ventral.
TS17: neural tube Present Regionally restricted 2D Expression is ventral.
TS17: head mesenchyme derived from neural crest Present Regionally restricted 2D Expression is in the craniofacial region.

Specimen 2E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: branchial arch ectoderm Strong Regionally restricted 2E Expression is in caudal regions.
TS17: Rathke's pouch Strong 2E
TS17: branchial arch endoderm Present 2E
TS17: cranial ganglion Present 2E
TS17: lung Present 2E
TS17: trigeminal ganglion Present 2E
TS17: stomach Present Regionally restricted 2E Expression is in the foregut endoderm of the future stomach.
TS17: brain Present Regionally restricted 2E Expression is ventral.
TS17: neural tube Present Regionally restricted 2E Expression is ventral.

Specimen 2F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: branchial arch ectoderm Strong Regionally restricted 2F Expression is in caudal regions.
TS17: lung Present 2F
TS17: stomach Present Regionally restricted 2F Expression is in the foregut endoderm of the future stomach.
TS17: otocyst Strong Regionally restricted 2F Expression is in the lateral regions.
TS17: brain Present Regionally restricted 2F Expression is ventral.
TS17: neural tube Present Regionally restricted 2F Expression is ventral.

Specimen 3A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: latero-nasal process ectoderm Strong 3A
TS19: medial-nasal process ectoderm Strong 3A
TS19: oral epithelium Strong 3A
TS19: head Present Regionally restricted 3A Expression is in the facial ectoderm.
TS19: branchial arch endoderm Present 3A
TS19: neural tube Present Regionally restricted 3A Expression is in the caudal regions of the neural tube.
TS19: tail neural tube Present Regionally restricted 3A Expression is in the caudal regions of the neural tube.
TS19: mandible primordium Present Regionally restricted 3A Expression is in the more cranial and caudal domains.
TS19: maxilla primordium Present Regionally restricted 3A Expression is in the more cranial and caudal domains.

Specimen 3B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: latero-nasal process ectoderm Strong 3B
TS19: medial-nasal process ectoderm Strong 3B
TS19: oral epithelium Strong 3B
TS19: head Present Regionally restricted 3B Expression is in the facial ectoderm.
TS19: branchial arch endoderm Present 3B
TS19: foregut duodenum Present 3B
TS19: heart atrium Present 3B
TS19: liver Present 3B
TS19: lung Present 3B
TS19: vertebral cartilage condensation Present 3B
TS19: neural tube Present Regionally restricted 3B Expression is in the caudal regions of the neural tube.
TS19: tail neural tube Present Regionally restricted 3B Expression is in the caudal regions of the neural tube.
TS19: mandible primordium Present Regionally restricted 3B Expression is in the more cranial and caudal domains.
TS19: maxilla primordium Present Regionally restricted 3B Expression is in the more cranial and caudal domains.

Specimen 4A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: nasal cavity epithelium Strong 4A

Specimen 4B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: nasal cavity epithelium Strong 4B

Specimen 4C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dental placode Strong Regionally restricted 4C Expression is in mandibular incisor tooth buds.
TS20: primary palate epithelium Strong 4C

Specimen 4D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: nasal cavity epithelium Strong 4D
TS20: primary palate epithelium Strong 4D

Specimen 4E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: nasal cavity epithelium Strong 4E
TS21: nasal septum Strong 4E

Specimen 4F: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: upper jaw incisor Strong 4F

Specimen 4G: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: palatal shelf epithelium Strong 4G

Specimen 4H: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: Meckel's cartilage Strong 4H
TS21: palatal shelf epithelium Strong 4H

Specimen 4I: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: palatal shelf epithelium Strong 4I
TS22: vomeronasal organ Present 4I

Specimen 4J: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: nasal septum Strong 4J
TS22: primary palate epithelium Present Regionally restricted 4J Expression is in the medial epithelial seam.

Specimen 4K: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: molar Strong 4K

Specimen 4L: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: basisphenoid cartilage condensation Present 4L
TS22: temporal bone petrous part Present 4L
TS22: vault of skull Present Regionally restricted 4L Expression is in mesenchyme.

Specimen 5A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: mandibular process Strong Regionally restricted 5A Expression is in the epithelial thickenings of future teeth.
TS19: maxillary process Strong Regionally restricted 5A Expression is in the epithelial thickenings of future teeth.
TS19: oral epithelium Strong Regionally restricted 5A Expression is in the epithelial thickenings of future teeth.

Specimen 5B: embryonic day 13.5 (more )
Note: Bud stage of tooth development.
Structure Level Pattern Image Note
TS21: tooth epithelium Present Regionally restricted 5B Expression is in basal regions of the tooth bud epithelium, adjacent to the dental papilla.

Specimen 5C: embryonic day 14.5 (more )
Note: Early cap stage of tooth development.
Structure Level Pattern Image Note
TS22: enamel organ Present 5C

Specimen 5D: embryonic day 15.5 (more )
Note: Late cap stage of tooth development.
Structure Level Pattern Image Note
TS23: enamel organ Present 5D

Specimen 5E: embryonic day 16.5 (more )
Note: Early bell stage of tooth development.
Structure Level Pattern Image Note
TS24: molar enamel organ Strong 5E

Specimen 5F: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: enamel organ Present Regionally restricted 5F Expression is in the internal enamel epithelium.

Specimen 5G: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: skin Present Regionally restricted 5G Expression is in the early epidermal placode

Specimen 5H: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: integumental system Present Regionally restricted 5H Expression is in the dermal papilla of the early hair follicle.

Specimen 5I: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: integumental system Present Regionally restricted 5I Expression is in the dermal papilla of the early hair follicle.

Specimen 5J: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: integumental system Strong Regionally restricted 5J Expression is in the dermal papilla of the early hair follicle and is weak in the more peripheral regions of the hair follicle, in the outer root sheath and hair matrix.

Specimen 5K: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hair follicle Strong Regionally restricted 5K Expression is in the dermal papilla of the early hair follicle and is weak in the more peripheral regions of the hair follicle, in the outer root sheath and hair matrix.
TS24: hair root sheath Weak 5K

Specimen 5L: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: hair follicle Strong Regionally restricted 5L Expression is in the dermal papilla of the early hair follicle and is weak in the more peripheral regions of the hair follicle, in the outer root sheath and hair matrix.
TS25: hair root sheath Weak 5L

Specimen 6A: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: rib Strong Regionally restricted 6A Expression is in the cartilaginous condensations.

Specimen 6B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: limb Strong Regionally restricted 6B Expression is in the cartilaginous skeleton.

Specimen 6C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: limb Strong Regionally restricted 6C Expression is in the cartilaginous skeleton.

Specimen 6D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lumbar vertebral cartilage condensation Present 6D

Specimen 6E: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: maturing glomerular tuft Present 6E


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory