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Pira12 Gene Detail
Summary
  • Symbol
    Pira12
  • Name
    paired-Ig-like receptor A12
  • Synonyms
    Gm14548
  • Feature Type
    protein coding gene
  • IDs
    MGI:3709645
    NCBI Gene: 100038909
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr7:3887241-3901119 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 2.24 cM
Strain
Comparison
more
  • SNPs within 2kb
    127 from dbSNP Build 142
  • Strain Annotations
    11
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3709645
 protein coding gene Chr7:3887200-3901158 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031535
 protein coding gene Chr7:814486-826420 (-)
A/J MGP_AJ_G0031506
 protein coding gene Chr7:617040-624862 (-)
AKR/J MGP_AKRJ_G0031436
 protein coding gene Chr7:814895-847808 (-)
BALB/cJ MGP_BALBcJ_G0031516
 protein coding gene Chr7:635951-791803 (-)
C3H/HeJ MGP_C3HHeJ_G0031237
 protein coding gene Chr7:644336-652074 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031978
 protein coding gene Chr7:849015-886746 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J MGP_DBA2J_G0031351
 protein coding gene Chr7:651522-659956 (-)
FVB/NJ MGP_FVBNJ_G0031303
 protein coding gene Chr7:586773-712825 (-)
LP/J MGP_LPJ_G0031440
 protein coding gene Chr7:918950-922859 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031346
 protein coding gene Chr7:916807-920706 (-)
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    LILRA1, leukocyte immunoglobulin like receptor A1
  • Vertebrate Orthologs
    9
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LILRA1, leukocyte immunoglobulin like receptor A1
  • Synonyms
    CD85I, LIR-6, LIR6
  • Links
    NCBI Gene ID: 11024
    neXtProt AC: NX_O75019
    UniProt: O75019

  • Chr Location
    19q13.42; chr19:54593582-54602381 (+)  GRCh38
  • Human Ortholog
    LILRA2, leukocyte immunoglobulin like receptor A2
  • Synonyms
    CD85H, ILT1, LIR-7, LIR7
  • Links
    NCBI Gene ID: 11027
    neXtProt AC: NX_Q8N149
    UniProt: Q8N149

  • Chr Location
    19q13.42; chr19:54572920-54590287 (+)  GRCh38
  • Human Ortholog
    LILRA3, leukocyte immunoglobulin like receptor A3
  • Synonyms
    CD85E, HM31, HM43, ILT-6, ILT6, LIR-4, LIR4
  • Links
    NCBI Gene ID: 11026
    neXtProt AC: NX_Q8N6C8
    UniProt: Q8N6C8

  • Chr Location
    19q13.4
  • Human Ortholog
    LILRA4, leukocyte immunoglobulin like receptor A4
  • Synonyms
    CD85g, ILT7
  • Links
    NCBI Gene ID: 23547
    neXtProt AC: NX_P59901
    UniProt: P59901

  • Chr Location
    19q13.42; chr19:54333185-54339162 (-)  GRCh38
  • Human Ortholog
    LILRA6, leukocyte immunoglobulin like receptor A6
  • Synonyms
    CD85b, ILT5, ILT-8, ILT8, LILRB3, LILRB6
  • Links
    NCBI Gene ID: 79168
    UniProt: Q6PI73

  • Chr Location
    19q13.42; chr19:54236590-54242790 (-)  GRCh38
  • Human Ortholog
    LILRB3, leukocyte immunoglobulin like receptor B3
  • Synonyms
    CD85A, HL9, ILT-5, ILT5, LILRA6, LIR-3, LIR3, PIR-B, PIRB
  • Links
    NCBI Gene ID: 11025
    neXtProt AC: NX_O75022
    UniProt: O75022

  • Chr Location
    19q13.42; chr19:54216278-54223506 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
  • All Sequences
    26
  • RefSeq
    10
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000074417 Ensembl Gene Model | MGI Sequence Detail 13879 C57BL/6J ±  kb
transcript ENSMUST00000070639 Ensembl | MGI Sequence Detail 2128 Not Applicable  
polypeptide ENSMUSP00000070073 Ensembl | MGI Sequence Detail 680 Not Applicable  
For the selected sequence
Protein
Information
less
Other
Accession IDs
less
MGI:6693729
References
more
  • Summaries
    All 10
    Gene Ontology 2
    Phenotypes 1
  • Earliest
    J:290663 Dai H, et al., PIRs mediate innate myeloid cell memory to nonself MHC molecules. Science. 2020 Jun 5;368(6495):1122-1127
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory