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Mir181d Gene Detail
Summary
  • Symbol
    Mir181d
  • Name
    microRNA 181d
  • Synonyms
    Mirn181d, mmu-mir-181d
Location &
Maps
more
  • Sequence Map
    Chr8:84905345-84905416 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 40.47 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    106 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3709847
 miRNA gene Chr8:84905345-84905416 (-)
129S1/SvImJ MGP_129S1SvImJ_G0009122
 miRNA gene Chr8:85053305-85053376 (-)
A/J MGP_AJ_G0009103
 miRNA gene Chr8:81723184-81723255 (-)
AKR/J MGP_AKRJ_G0009094
 miRNA gene Chr8:84138215-84138286 (-)
BALB/cJ MGP_BALBcJ_G0009088
 miRNA gene Chr8:81828966-81829037 (-)
C3H/HeJ MGP_C3HHeJ_G0009027
 miRNA gene Chr8:84747874-84747945 (-)
C57BL/6NJ MGP_C57BL6NJ_G0009328
 miRNA gene Chr8:88320501-88320572 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0008197
 miRNA gene Chr8:75520092-75520163 (-)
CAST/EiJ MGP_CASTEiJ_G0008862
 miRNA gene Chr8:84172351-84172422 (-)
CBA/J MGP_CBAJ_G0008996
 miRNA gene Chr8:91422685-91422756 (-)
DBA/2J MGP_DBA2J_G0009026
 miRNA gene Chr8:81360516-81360587 (-)
FVB/NJ MGP_FVBNJ_G0009044
 miRNA gene Chr8:80288456-80288527 (-)
LP/J MGP_LPJ_G0009122
 miRNA gene Chr8:85163790-85163861 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0009009
 miRNA gene Chr8:93932338-93932409 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0009299
 miRNA gene Chr8:84117582-84117653 (-)
PWK/PhJ MGP_PWKPhJ_G0008789
 miRNA gene Chr8:80586332-80586403 (-)
SPRET/EiJ MGP_SPRETEiJ_G0008631
 miRNA gene Chr8:82931419-82931490 (-)
WSB/EiJ MGP_WSBEiJ_G0008957
 miRNA gene Chr8:84526148-84526219 (-)



Homology
more
  • Human Ortholog
    MIR181D, microRNA 181d
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR181D, microRNA 181d
  • Synonyms
    mir-181d, MIRN181D
  • Links
    NCBI Gene ID: 574457

  • Chr Location
    chr19:13874875-13875011 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 2 alleles in 1 genetic background
    1 phenotype from multigenic genotypes
    34 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit increased elevated percentage of T cells in the spleen.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    709
  • Tissues
    3
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      23
    • RefSeq
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 100049549 NCBI Gene Model | MGI Sequence Detail 72 C57BL/6J ±  kb
    transcript NR_030534 RefSeq | MGI Sequence Detail 72 C57BL/6  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 3
      Primer pair 2
      Other 1
    Other Database
    Links
    less
    miRBase MI0005450
    References
    more
    • Summaries
      All 51
      Developmental Gene Expression 3
      Gene Ontology 4
      Phenotypes 34
    • Earliest
      J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54(1):113-145
    • Latest
      J:348117 Okuma H, et al., N-terminal domain on dystroglycan enables LARGE1 to extend matriglycan on alpha-dystroglycan and prevents muscular dystrophy. Elife. 2023 Feb 1;12
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory