Ncaph2<nes> Chemically induced Allele Detail MGI Mouse (MGI:3710093)

Ncaph2^nes
Chemically induced Allele Detail

Summary

Symbol:	Ncaph2^nes
Name:	non-SMC condensin II complex, subunit H2; nessy
MGI ID:	MGI:3710093
Synonyms:	kleisin beta^nes, Ncaph2^I15N, nes
Gene:	Ncaph2 Location: Chr15:89239922-89257029 bp, + strand Genetic Position: Chr15, 44.84 cM
Alliance:	Ncaph2^nes page

Mutation
origin

Strain of Origin:	C57BL/6JSfdAnu
Project Collection:	APF ENU Mutagenesis

Mutation
description

Allele Type:		Chemically induced (ENU) (Hypomorph)
Mutation:		Single point mutation
		Mutation details: T to A substitution in exon 1 at 44th base following the first ATG (note that there are two ATG transcriptional start sites for this gene, resulting in three alternate amino acid sequences for exon 1) (J:123300)
Inheritance:		Recessive

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available Cell Lines: 0 lines available
Carrying any Ncaph2 Mutation:	38 strains or lines available

References

Original:	J:123300 Gosling KM, et al., A mutation in a chromosome condensin II subunit, kleisin beta, specifically disrupts T cell development. Proc Natl Acad Sci U S A. 2007 Jul 24;104(30):12445-50
All:	5 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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