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Tg(Nppa-cre)4Vmc
Transgene Detail
Summary
Symbol: Tg(Nppa-cre)4Vmc
Name: transgene insertion 4, Vincent M Christoffels
MGI ID: MGI:3710255
Synonyms: Nppa-cre4
Transgene: Tg(Nppa-cre)4Vmc  Location: unknown  
Alliance: Tg(Nppa-cre)4Vmc page
Transgene
origin
Strain of Origin:  Not Applicable
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Nppa-cre)4Vmc expression driven by 1 gene
 
Mutation details: The transgenic construct consisted of a sequence fragment encoding cre recombinase, a nuclear localization signal, and a consensus Kozak signal inserted at the start codon of the mouse genomic Nppa sequence. The 0.7 kbp Nppa proximal promoter region (-3kbp to +4 kbp relative to the transcription start site) was included. The mouse Nppa proximal promoter drives expression of cre recombinase in atrial cardiomyocytes beginning around E10.5. Complete expression is observed around E14.5. Some expression was observed in the inflow tract. (J:86158)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Nppa (mouse)
Summary of all recombinase alleles driven by Nppa.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:86158 de Lange FJ, et al., Atrial cardiomyocyte-specific expression of Cre recombinase driven by an Nppa gene fragment. Genesis. 2003 Sep;37(1):1-4
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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11/19/2024
MGI 6.24 		The Jackson Laboratory