Gas1<tm2Fan> Targeted Allele Detail MGI Mouse (MGI:3711070)

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Gas1^tm2Fan
Targeted Allele Detail

Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Summary

Symbol:	Gas1^tm2Fan
Name:	growth arrest specific 1; targeted mutation 1, Chen-Ming Fan
MGI ID:	MGI:3711070
Synonyms:	Gas1^-, Gas1^LacZ
Gene:	Gas1 Location: Chr13:60322219-60325179 bp, - strand Genetic Position: Chr13, 31.92 cM, cytoband B3-C2
Alliance:	Gas1^tm2Fan page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:121554
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Mutation
description

Allele Type:		Targeted (Null/knockout, Reporter)
Mutations:		Insertion, Intragenic deletion
		The coding sequence was replaced by a tau-lacZ gene with a PGK-neo cassette. (J:121554)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:	102 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	8 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Gas1 Mutation:	14 strains or lines available

References

Original:	J:121554 Martinelli DC, et al., Gas1 extends the range of Hedgehog action by facilitating its signaling. Genes Dev. 2007 May 15;21(10):1231-43
All:	16 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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