Tg(GFAP-cre/PGR*)2Kdmc
Transgene Detail
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| Symbol: |
Tg(GFAP-cre/PGR*)2Kdmc |
| Name: |
transgene insertion 2, Ken D McCarthy |
| MGI ID: |
MGI:3712448 |
| Synonyms: |
CrePR2, hGFAP-CrePR2, Tg(GFAP-cre)2Kdmc, Tg(GFAP-cre/PGR)2Kdmc |
| Transgene: |
Tg(GFAP-cre/PGR*)2Kdmc Location: unknown
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| Alliance: |
Tg(GFAP-cre/PGR*)2Kdmc page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Inducible, Recombinase) |
| Inducer: |
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mifepristone |
| Mutation: |
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Insertion
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Tg(GFAP-cre/PGR*)2Kdmc expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Homolog in Mouse |
Note |
| human |
GFAP (2670) |
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Mutation details: Cre recombinase cDNA with the progesterone receptor was placed under the control of the human glial fibrillary acidic protein promoter. None of the 4 lines that expressed cre/PGR mRNA exhibited inducible recombinase activity after RU486 induction in crosses with reporter mice, so the lines were discontinued.
(J:121777)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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GFAP
(human)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:121777 Casper KB, et al., Characterization of astrocyte-specific conditional knockouts. Genesis. 2007 May;45(5):292-9 |
| All: |
1 reference(s) |
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Analysis Tools
