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Cul3tm1Jdsr
Targeted Allele Detail
Summary
Symbol: Cul3tm1Jdsr
Name: cullin 3; targeted mutation 1, Jeffrey D Singer
MGI ID: MGI:3714267
Synonyms: Cul3flox
Gene: Cul3  Location: Chr1:80242640-80318197 bp, - strand  Genetic Position: Chr1, 41.24 cM, cytoband C4
Alliance: Cul3tm1Jdsr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:122228
Parent Cell Line:  AK7 (ES Cell)
Strain of Origin:  129S4/SvJaeSor
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Exons 4-7 were flanked with loxP sites. An FRT-flanked neo was included in intron 3. (J:122228)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 8 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cul3 Mutation:  51 strains or lines available
References
Original:  J:122228 McEvoy JD, et al., Constitutive turnover of cyclin E by Cul3 maintains quiescence. Mol Cell Biol. 2007 May;27(10):3651-66
All:  10 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory