Map2k1<tm1Chrn> Targeted Allele Detail MGI Mouse (MGI:3714918)

Map2k1^tm1Chrn
Targeted Allele Detail

Summary

Symbol:	Map2k1^tm1Chrn
Name:	mitogen-activated protein kinase kinase 1; targeted mutation 1, Jean Charron
MGI ID:	MGI:3714918
Synonyms:	Map2k1^floxed, Mek1^fl
Gene:	Map2k1 Location: Chr9:64093066-64160887 bp, - strand Genetic Position: Chr9, 34.55 cM
Alliance:	Map2k1^tm1Chrn page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:112223
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Mutation
description

Allele Type:		Targeted (Conditional ready, No functional change)
Mutation:		Insertion
		Exon 3 is floxed and can be removed by Cre recombination to create a null allele. (J:112223)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:

5 RNA-Seq or microarray experiment(s)

Tumor Data

List all tumor models in MMHCdb carrying Map2k1^tm1Chrn

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Map2k1 Mutation:	94 strains or lines available

References

Original:	J:112223 Bissonauth V, et al., Requirement for Map2k1 (Mek1) in extra-embryonic ectoderm during placentogenesis. Development. 2006 Sep;133(17):3429-40
All:	34 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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