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Mesp2tm13(cre/Esr1*)Ysa
Targeted Allele Detail
Summary
Symbol: Mesp2tm13(cre/Esr1*)Ysa
Name: mesoderm posterior 2; targeted mutation 13, Yumiko Saga
MGI ID: MGI:3715268
Synonyms: Mesp2neo-MCM, Mesp2tm13(cre/Esr1)Ysa
Gene: Mesp2  Location: Chr7:79460475-79463179 bp, + strand  Genetic Position: Chr7, 45.18 cM
Alliance: Mesp2tm13(cre/Esr1*)Ysa page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:122532
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutations:    Insertion, Intragenic deletion
 
Mesp2tm13(cre/Esr1*)Ysa expression driven by 1 gene
 
Mutation details: A floxed-neo and cre recombinase/mutant estrogen receptor ligand binding domain fusion cassette replaces the entire open reading frame. However, no cre expression is detected. (J:122532)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Mesp2 (mouse)
Summary of all recombinase alleles driven by Mesp2.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mesp2 Mutation:  30 strains or lines available
References
Original:  J:122532 Takahashi Y, et al., Appropriate suppression of Notch signaling by Mesp factors is essential for stripe pattern formation leading to segment boundary formation. Dev Biol. 2007 Apr 15;304(2):593-603
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory