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Bsxtm1Tre
Targeted Allele Detail
Summary
Symbol: Bsxtm1Tre
Name: brain specific homeobox; targeted mutation 1, Mathias Treier
MGI ID: MGI:3716209
Synonyms: BsxHD
Gene: Bsx  Location: Chr9:40785423-40791353 bp, + strand  Genetic Position: Chr9, 21.65 cM
Alliance: Bsxtm1Tre page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:122746
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe lacZ coding sequence was inserted with a neomycin resistance cassette in frame, thereby deleting part of exon 2. This exon encodes helix 1 and 2 of the homeodomain. (J:122746)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bsx Mutation:  19 strains or lines available
References
Original:  J:122746 Sakkou M, et al., A role for brain-specific homeobox factor bsx in the control of hyperphagia and locomotory behavior. Cell Metab. 2007 Jun;5(6):450-63
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory