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Angptl4tm1Lex
Targeted Allele Detail
Summary
Symbol: Angptl4tm1Lex
Name: angiopoietin-like 4; targeted mutation 1, Lexicon Genetics
MGI ID: MGI:3716688
Synonyms: Angptl4-
Gene: Angptl4  Location: Chr17:33993874-34000549 bp, - strand  Genetic Position: Chr17, 17.98 cM
Alliance: Angptl4tm1Lex page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:122968
Parent Cell Line:  Lex-1 (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A targeting vector was designed to replace exons 2 and 3 with a neomycin resistance gene. (J:122968)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Angptl4 Mutation:  34 strains or lines available
References
Original:  J:122968 Desai U, et al., Lipid-lowering effects of anti-angiopoietin-like 4 antibody recapitulate the lipid phenotype found in angiopoietin-like 4 knockout mice. Proc Natl Acad Sci U S A. 2007 Jul 10;104(28):11766-71
All:  5 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory