Ar<tm1Jdz> Targeted Allele Detail MGI Mouse (MGI:3717246)

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Ar^tm1Jdz
Targeted Allele Detail

Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Summary

Symbol:	Ar^tm1Jdz
Name:	androgen receptor; targeted mutation 1, Jeffrey D Zajac
MGI ID:	MGI:3717246
Synonyms:	ARf^Ex3, ARflox, AR^lox
Gene:	Ar Location: ChrX:97192375-97366821 bp, + strand Genetic Position: ChrX, 42.82 cM
Alliance:	Ar^tm1Jdz page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:123057
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129X1/SvJ

Mutation
description

Allele Type:		Targeted (Conditional ready, No functional change)
Mutation:		Insertion
		A loxP site was inserted into intron 2 and a floxed neo cassette was inserted into intron 3. (J:123057)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:	3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	14 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Ar Mutation:	23 strains or lines available

References

Original:	J:123057 Notini AJ, et al., Genomic actions of the androgen receptor are required for normal male sexual differentiation in a mouse model. J Mol Endocrinol. 2005 Dec;35(3):547-55
All:	27 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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