Tg(Pou1f1-cre,-ALPP)1Xdfu
Transgene Detail
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| Symbol: |
Tg(Pou1f1-cre,-ALPP)1Xdfu |
| Name: |
transgene insertion 1, Xiang-Dong Fu |
| MGI ID: |
MGI:3719216 |
| Synonyms: |
Pit-1-Cre/hpAP |
| Transgene: |
Tg(Pou1f1-cre,-ALPP)1Xdfu Location: unknown
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| Alliance: |
Tg(Pou1f1-cre,-ALPP)1Xdfu page
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| Strain of Origin: |
Not Applicable
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(Pou1f1-cre,-ALPP)1Xdfu expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| Not Specified |
Pou1f1 |
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Mutation details: This transgene was designed to express cre recombinase during pituitary developmental stages starting at e13.5, using a 15.5 kb POU domain, class 1, transcription factor 1 (Pit1, growth hormone factor 1) promoter. An IRES separated the cre cDNA from the human placenta alkaline phosphatase gene and polyA signal. The promoter is capable of driving expression in all three cell lineages: the somatotrophs, lactotrophs and thyrotrophs.
(J:123618)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Pou1f1
(species not specified)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:123618 Xiao R, et al., Splicing regulator SC35 is essential for genomic stability and cell proliferation during mammalian organogenesis. Mol Cell Biol. 2007 Aug;27(15):5393-402 |
| All: |
1 reference(s) |
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Analysis Tools
