Lhx1<tm4Bhr> Targeted Allele Detail MGI Mouse (MGI:3719681)

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Lhx1^tm4Bhr
Targeted Allele Detail

Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Summary

Symbol:	Lhx1^tm4Bhr
Name:	LIM homeobox protein 1; targeted mutation 4, Richard R Behringer
MGI ID:	MGI:3719681
Synonyms:	Lhx1^fx1
Gene:	Lhx1 Location: Chr11:84409110-84416361 bp, - strand Genetic Position: Chr11, 51.31 cM
Alliance:	Lhx1^tm4Bhr page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:123471
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation
description

Allele Type:		Targeted (Conditional ready, No functional change)
Mutation:		Insertion
		Mutation details: A loxP site was inserted into the first intron and a floxed neo cassette was inserted into the fourth intron. (J:123471)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Lhx1 Mutation:	22 strains or lines available

References

Original:	J:123471 Zhao Y, et al., LIM-homeodomain proteins Lhx1 and Lhx5, and their cofactor Ldb1, control Purkinje cell differentiation in the developing cerebellum. Proc Natl Acad Sci U S A. 2007 Aug 7;104(32):13182-6
All:	1 reference(s)

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