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Aicdatm1(cre)Mnz
Targeted Allele Detail
Summary
Symbol: Aicdatm1(cre)Mnz
Name: activation-induced cytidine deaminase; targeted mutation 1, Michel C Nussenzweig
MGI ID: MGI:3720568
Synonyms: AID-, AID Cre, AIDCre
Gene: Aicda  Location: Chr6:122530768-122541139 bp, + strand  Genetic Position: Chr6, 57.65 cM, cytoband F2
Alliance: Aicdatm1(cre)Mnz page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:153206
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Aicdatm1(cre)Mnz expression driven by 1 gene
 
Mutation details: A targeting vector containing Cre, an FRT-flanked neomycin resistance cassette, and a DTA (diphtheria toxin) gene was used to replace exon 1 of the gene. (J:145691, J:153206)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Aicda (mouse)
Summary of all recombinase alleles driven by Aicda.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Tumor Data
List all tumor models in MMHCdb carrying Aicdatm1(cre)Mnz
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Aicda Mutation:  57 strains or lines available
References
Original:  J:153206 Nussenzweig MC, Generation of an Aicda knock-in cre allele. MGI Direct Data Submission. 2009;
All:  52 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory