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Cpa1tm1(cre/ERT2)Dam
Targeted Allele Detail
Summary
Symbol: Cpa1tm1(cre/ERT2)Dam
Name: carboxypeptidase A1, pancreatic; targeted mutation 1, Douglas A Melton
MGI ID: MGI:3720733
Synonyms: Cp1aCreERT2, Cpa1tm1(cre/ESR1)Dam, proCPA1CreERT2
Gene: Cpa1  Location: Chr6:30639217-30645360 bp, + strand  Genetic Position: Chr6, 12.52 cM, cytoband B1
Alliance: Cpa1tm1(cre/ERT2)Dam page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:123923
Parent Cell Line:  AV3 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Cpa1tm1(cre/ERT2)Dam expression driven by 1 gene
 
Mutation details: A CreERT2-IRES-H2BYFP-ACN cassette was inserted into the locus to replace the first 11 amino acids of the coding region. (J:123923)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cpa1 (mouse)
Summary of all recombinase alleles driven by Cpa1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cpa1 Mutation:  25 strains or lines available
References
Original:  J:123923 Zhou Q, et al., A multipotent progenitor domain guides pancreatic organogenesis. Dev Cell. 2007 Jul;13(1):103-14
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory