Cdk5<tm1Bibb> Targeted Allele Detail MGI Mouse (MGI:3720892)

Cdk5^tm1Bibb
Targeted Allele Detail

Summary

Symbol:	Cdk5^tm1Bibb
Name:	cyclin dependent kinase 5; targeted mutation 1, James A Bibb
MGI ID:	MGI:3720892
Synonyms:	fCDK5
Gene:	Cdk5 Location: Chr5:24623239-24628528 bp, - strand Genetic Position: Chr5, 11.73 cM, cytoband A3-B1
Alliance:	Cdk5^tm1Bibb page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:124046
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Mutation
description

Allele Type:		Targeted (Conditional ready, No functional change)
Mutation:		Insertion
		Mutation details: LoxP sites were inserted to flank exons 2-5, the exons encoding the vital catalytic-domain components. (J:124046)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:

12 assay results

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Cdk5 Mutation:	17 strains or lines available

References

Original:	J:124046 Hawasli AH, et al., Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation. Nat Neurosci. 2007 Jul;10(7):880-6
All:	18 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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