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Tg(Ins2-cre/ERT)1Dam
Transgene Detail
Summary
Symbol: Tg(Ins2-cre/ERT)1Dam
Name: transgene insertion 1, Douglas A Melton
MGI ID: MGI:3720973
Synonyms: RIP-CreER, Tg(Ins2-cre/Esr1)1Dam
Transgene: Tg(Ins2-cre/ERT)1Dam  Location: unknown  
Alliance: Tg(Ins2-cre/ERT)1Dam page
Transgene
origin
Strain of Origin:  (C57BL/6 x CBA)F1
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Ins2-cre/ERT)1Dam expression driven by 1 gene
    The rat insulin promoter was used to drive the expression of tamoxifen-dependent cre recombinase. (J:124161)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Ins2 (rat)
Summary of all recombinase alleles driven by Ins2.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:124161 Dor Y, et al., Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. Nature. 2004 May 6;429(6987):41-6
All:  56 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory