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Tg(Col2a1-cre/ERT)1Flng
Transgene Detail
Summary
Symbol: Tg(Col2a1-cre/ERT)1Flng
Name: transgene insertion 1, Fanxin Long
MGI ID: MGI:3721223
Synonyms: Col2-creTM
Transgene: Tg(Col2a1-cre/ERT)1Flng  Location: unknown  
Alliance: Tg(Col2a1-cre/ERT)1Flng page
Transgene
origin
Strain of Origin:  (C57BL/6J x CBA/J)F1
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Col2a1-cre/ERT)1Flng expression driven by 1 gene
 
Mutation detailsThe procollagen, type II, alpha 1 promoter was used to drive expression of cre recombinase in chondrocytes versus perichondrial cells upon proper administration of tamoxifen. (J:123971)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Col2a1 (species not specified)
Summary of all recombinase alleles driven by Col2a1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:123971 Hilton MJ, et al., Tamoxifen-inducible gene deletion reveals a distinct cell type associated with trabecular bone, and direct regulation of PTHrP expression and chondrocyte morphology by Ihh in growth region cartilage. Dev Biol. 2007 Aug 1;308(1):93-105
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory