Tamalintm1.1Nak
Targeted Allele Detail
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| Symbol: |
Tamalintm1.1Nak |
| Name: |
trafficking regulator and scaffold protein tamalin; targeted mutation 1.1, Shigetada Nakanishi |
| MGI ID: |
MGI:3723519 |
| Synonyms: |
Tam- |
| Gene: |
Tamalin Location: Chr15:101122088-101130637 bp, + strand Genetic Position: Chr15, 56.57 cM, cytoband F3
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| Alliance: |
Tamalintm1.1Nak page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:124994
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| Parent Cell Line: |
CCE/EK.CCE (ES Cell)
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| Strain of Origin: |
129S/SvEv-Gpi1c
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutation: |
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Intragenic deletion
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Mutation details: Using a targeting vector constructed with 129/Sv mouse DNA, a floxed neo cassette was inserted upstream of exon 5 and an additional lox P site was inserted downstream of exon 7. Cre-mediated recombination removed the neo cassette and exons 5 through 7 to create a truncated protein detectable by western blot analysis that lacks a complete PDZ dmain and leucine zipper.
(J:124994)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Tamalin Mutation: |
15 strains or lines available
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| Original: |
J:124994 Ogawa M, et al., Altered sensitivities to morphine and cocaine in scaffold protein tamalin knockout mice. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14789-94 |
| All: |
1 reference(s) |
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Analysis Tools
