Tg(Apoc3)5381Bres
Transgene Detail
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Symbol: |
Tg(Apoc3)5381Bres |
Name: |
transgene insertion 5381, Jan L Breslow |
MGI ID: |
MGI:3758464 |
Synonyms: |
MoCIIITg |
Transgene: |
Tg(Apoc3)5381Bres Location: unknown
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Alliance: |
Tg(Apoc3)5381Bres page
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Strain of Origin: |
C57BL/6 x CBA
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(Apoc3)5381Bres expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Note |
mouse |
Apoc3 (MGI:88055) |
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Mutation details: A genomic construct containing a 4.7 kb Xbal-Xbal fragment, which includes the entire mouse
apoC-III gene plus 2 kb of 5' and 1 kb of 3' sequence, was used for the transgene. Northern blot and densitometry analysis showed that Apoc3 mRNA was increased 4-fold in liver and 5-fold in the intestine.
(J:34875)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:34875 Aalto-Setala K, et al., Further characterization of the metabolic properties of triglyceride-rich lipoproteins from human and mouse apoC-III transgenic mice. J Lipid Res. 1996 Aug;37(8):1802-11 |
All: |
1 reference(s) |
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