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Mycbp2tm1.1Adia
Targeted Allele Detail
Summary
Symbol: Mycbp2tm1.1Adia
Name: MYC binding protein 2, E3 ubiquitin protein ligase; targeted mutation 1.1, Aaron DiAntonio
MGI ID: MGI:3760640
Synonyms: Phr1delta8,9
Gene: Mycbp2  Location: Chr14:103350847-103584250 bp, - strand  Genetic Position: Chr14, 51.79 cM
Alliance: Mycbp2tm1.1Adia page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:125702
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExons 8 and 9 were removed by cre-mediated recombination following a cross with Tg(ACTB-cre)2Mrt mice. RT-PCR was performed to confirm the removal of the exons. (J:125702)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 15 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mycbp2 Mutation:  224 strains or lines available
References
Original:  J:125702 Bloom AJ, et al., The requirement for Phr1 in CNS axon tract formation reveals the corticostriatal boundary as a choice point for cortical axons. Genes Dev. 2007 Oct 15;21(20):2593-606
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory