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Tg(Nes-cre/Esr1*)4Ynj
Transgene Detail
Summary
Symbol: Tg(Nes-cre/Esr1*)4Ynj
Name: transgene insertion 4, Yuh-Nung Jan
MGI ID: MGI:3765946
Synonyms: nestin-creERtm, Tg(Nes-cre/Esr1)4Ynj
Transgene: Tg(Nes-cre/Esr1*)4Ynj  Location: unknown  
Alliance: Tg(Nes-cre/Esr1*)4Ynj page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Nes-cre/Esr1*)4Ynj expression driven by 1 gene
 
Mutation details: The targeting construct contains the tamoxifen-inducible cre/Esr1 sequence under the control of the rat Nestin promoter. Line 4 shows postnatally inducible cre activity, in addition to inducible embryonic brain and spinal cord activity assayed by crossing the mice to mice carrying the ROSA26 reporter. (J:127227)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Nes (rat)
Summary of all recombinase alleles driven by Nes.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:127227 Kuo CT, et al., Postnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic niche. Cell. 2006 Dec 15;127(6):1253-64
All:  19 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory