Tg(Ascl1-cre/Esr1*)1Jejo
Transgene Detail
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| Symbol: |
Tg(Ascl1-cre/Esr1*)1Jejo |
| Name: |
transgene insertion 1, Jane Johnson |
| MGI ID: |
MGI:3767428 |
| Synonyms: |
Ascl1-CreERTM, line B2C-6, Mash1BAC-CreER, Tg(Ascl1-cre/ESR1)1Jejo |
| Transgene: |
Tg(Ascl1-cre/Esr1*)1Jejo Location: unknown
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| Alliance: |
Tg(Ascl1-cre/Esr1*)1Jejo page
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| Transgene Type: |
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Transgenic (Inducible, Recombinase) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Tg(Ascl1-cre/Esr1*)1Jejo expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| Not Specified |
Ascl1 |
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Mutation details: The transgene contains a BAC in which the Ascl1 open reading frame is replaced with a cre-estrogen response element fusion. Expression of cre, detected following a cross to a reporter strain, is restricted to the midbrain at E10.5, the developing sympathetic neurons at E10.5 and E11.5, the enteric nervous system, diencephalon and hindbrain at E11.5, and the dorsal neural tube at E12.5 reflecting the endogenous expression pattern of the gene. Two lines were established (B2C-6 and B2C-8). B2C-6 was analyzed in more detail and is represented by line 1 here.
(J:117032)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Ascl1
(species not specified)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:117032 Battiste J, et al., Ascl1 defines sequentially generated lineage-restricted neuronal and oligodendrocyte precursor cells in the spinal cord. Development. 2007 Jan;134(2):285-93 |
| All: |
19 reference(s) |
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Analysis Tools
