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Tg(Ascl1-EGFP,-cre)1Jejo
Transgene Detail
Summary
Symbol: Tg(Ascl1-EGFP,-cre)1Jejo
Name: transgene insertion 1, Jane Johnson
MGI ID: MGI:3767431
Synonyms: Ascl1-GIC, M1-GIC, Tg(RPCI-428P21-EGFP,-cre)1Jejo
Transgene: Tg(Ascl1-EGFP,-cre)1Jejo  Location: unknown  
Alliance: Tg(Ascl1-EGFP,-cre)1Jejo page
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA)F1
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Ascl1-EGFP,-cre)1Jejo expression driven by 1 gene
 
Mutation details: The transgene is a bacterial artificial chromosome (BAC), RPCI-428P2, bearing a 305 kb mouse genomic segment that contains the Ascl1 locus(98 kb of 5' and 206 kb of 3' of the start codon), in which the coding sequence of the gene has been replaced with an EGFP-IRES-CRE cassette. The GFP reporter expression is low but reflects the Ascl1 pattern throughout multiple stages and in multiple regions, including the caudal neural tube, the telencephalon and diencephalon, and sympathetic and enteric nervous systems. (J:98830, J:117032)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Ascl1 (mouse)
Summary of all recombinase alleles driven by Ascl1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:98830 Helms AW, et al., Sequential roles for Mash1 and Ngn2 in the generation of dorsal spinal cord interneurons. Development. 2005 Jun;132(12):2709-19
All:  8 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory