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Tg(Nes-cre/ERT2)KEisc
Transgene Detail
Summary
Symbol: Tg(Nes-cre/ERT2)KEisc
Name: transgene insertion K, Amelia Eisch
MGI ID: MGI:3767432
Synonyms: Nestin-CreERT2, Tg(Nes-cre/ERT2)KJejo, Tg(Nes-cre/ESR1)KJejo, Tg(Nes-cre)KJejo
Transgene: Tg(Nes-cre/ERT2)KEisc  Location: unknown  
Alliance: Tg(Nes-cre/ERT2)KEisc page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Nes-cre/ERT2)KEisc expression driven by 1 gene
 
Mutation details: The Nestin-cre/ERT2 transgene was designed with the rat nestin (Nes) promoter driving expression of a CreERT2 fusion gene (cre/ERT2; Cre recombinase fused to a G400V/M543A/L544A triple mutation of the human estrogen receptor ligand-binding domain). The transgene was microinjected into fertilized C57BL/6J oocytes, and line K was established. (J:117032, J:141562)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Nes (rat)
Summary of all recombinase alleles driven by Nes.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:117032 Battiste J, et al., Ascl1 defines sequentially generated lineage-restricted neuronal and oligodendrocyte precursor cells in the spinal cord. Development. 2007 Jan;134(2):285-93
All:  141 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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11/12/2024
MGI 6.24 		The Jackson Laboratory