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Bcl11btm1Avram
Targeted Allele Detail
Summary
Symbol: Bcl11btm1Avram
Name: B cell leukemia/lymphoma 11B; targeted mutation 1, Dorina Avram
MGI ID: MGI:3767620
Synonyms: BCL11BF
Gene: Bcl11b  Location: Chr12:107876662-107969861 bp, - strand  Genetic Position: Chr12, 59.1 cM, cytoband F1
Alliance: Bcl11btm1Avram page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:128515
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Exon 3, which includes most of the gene's coding sequence, was flanked by LoxP sites. (J:128515)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bcl11b Mutation:  46 strains or lines available
References
Original:  J:128515 Albu DI, et al., BCL11B is required for positive selection and survival of double-positive thymocytes. J Exp Med. 2007 Nov 26;204(12):3003-15
All:  10 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory