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Tbx3tm1Jcib
Targeted Allele Detail
Summary
Symbol: Tbx3tm1Jcib
Name: T-box 3; targeted mutation 1, Juan Carlos Belmonte
MGI ID: MGI:3769504
Synonyms: Tbx3neo
Gene: Tbx3  Location: Chr5:119808734-119822789 bp, + strand  Genetic Position: Chr5, 60.34 cM
Alliance: Tbx3tm1Jcib page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:129349
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Part of exon 1 was replaced with a neo cassette with several stop codons. (J:129349)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 11 assay results
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tbx3 Mutation:  49 strains or lines available
References
Original:  J:129349 Ribeiro I, et al., Tbx2 and Tbx3 regulate the dynamics of cell proliferation during heart remodeling. PLoS One. 2007;2(4):e398
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory