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Tg(Slc6a3-icre)#Gsc
Transgene Detail
Summary
Symbol: Tg(Slc6a3-icre)#Gsc
Name: transgene insertion, Gunther Schutz
MGI ID: MGI:3770171
Synonyms: DATCre, Tg(Slc6a3-cre)1Gsc
Transgene: Tg(Slc6a3-icre)#Gsc  Location: unknown  
Alliance: Tg(Slc6a3-icre)#Gsc page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Slc6a3-icre)#Gsc expression driven by 1 gene
 
Mutation detailsThe improved codon cre open reading frame was inserted at the translation initiation site of Slc6a3 to create a transgene that drives expression of cre in the brain. Lines 9075 (2 copies of the transgene), 9190 (3 copies) and 9140 (5 copies) were generated. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:114551)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Slc6a3 (species not specified)
Summary of all recombinase alleles driven by Slc6a3.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:114551 Parlato R, et al., Survival of DA neurons is independent of CREM upregulation in absence of CREB. Genesis. 2006 Oct;44(10):454-64
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory