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Bnc1tm1.1Tsen
Targeted Allele Detail
Summary
Symbol: Bnc1tm1.1Tsen
Name: basonuclin zinc finger protein 1; targeted mutation 1.1, Hung Tseng
MGI ID: MGI:3771811
Synonyms: Bnc1-
Gene: Bnc1  Location: Chr7:81616401-81642047 bp, - strand  Genetic Position: Chr7, 45.71 cM
Alliance: Bnc1tm1.1Tsen page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:130266
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation details: Exon 4 was removed by germ-line, cre-mediated recombination resulting a premature stop codon and a frame shift. The absence of transcript was confirmed by RT-PCR and the absence of protein product was confirmed by immunohistochemistry. (J:130266)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bnc1 Mutation:  29 strains or lines available
References
Original:  J:130266 Zhang X, et al., Basonuclin-null mutation impairs homeostasis and wound repair in mouse corneal epithelium. PLoS One. 2007;2(10):e1087
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory