Results
|
Specimen
1A:
embryonic day 7.5
(more )
Specimen
1A:
(close )
Genetic Background:
|
NMRI
|
Age:
|
embryonic day 7.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
Not shown:
embryonic day 8.5
(more )
Specimen
Not shown:
(close )
Genetic Background:
|
NMRI
|
Age:
|
embryonic day 8.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS13: embryo |
Present |
|
|
Expression is ubiquitous; there is no tissue-specific expression at this age.
|
Specimen
Not shown:
embryonic day 9.5
(more )
Specimen
Not shown:
(close )
Genetic Background:
|
NMRI
|
Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: embryo |
Present |
|
|
Expression is ubiquitous; there is no tissue-specific expression at this age.
|
Specimen
1B:
embryonic day 10.5
(more )
Specimen
1B:
(close )
Genetic Background:
|
NMRI
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: embryo |
Present |
|
1B PKC i/l
|
Expression is ubiquitous; there is no tissue-specific expression at this age.
|
Specimen
2:
embryonic day 12.5
(more )
Specimen
2:
(close )
Genetic Background:
|
NMRI
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Fresh Frozen
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: embryo |
Present |
|
2A
|
There is extensive expression throughout the embryo with regionalization in certain tissues.
|
TS20: corpus striatum |
Strong |
|
2A
|
|
TS20: midbrain |
Strong |
|
2A
|
|
TS20: olfactory epithelium |
Strong |
|
2C
,
2A
|
|
TS20: neocortex |
Strong |
|
2A
,
2E
|
|
TS20: choroid plexus |
Strong |
|
2A
,
2G
|
|
TS20: medulla oblongata |
Strong |
|
2A
,
2G
|
|
TS20: adenohypophysis |
Strong |
|
2A
,
2I
|
There is strong expression in Rathke's pouch.
|
TS20: diencephalon |
Strong |
|
2I
,
2A
|
|
TS20: liver |
Strong |
|
2A
,
2K
|
|
TS20: lung |
Present |
|
2M
,
2A
|
Expression is ubiquitous.
|
TS20: lobar bronchus |
Present |
|
2A
,
2M
|
Expression levels are elevated in the segmental bronchi.
|
TS20: intestine |
Strong |
|
2O
,
2A
|
There is strong expression in all layers.
|
TS20: metanephros |
Present |
|
2Q
,
2A
|
|
TS20: stomach |
Present |
|
2Q
,
2A
|
|
TS20: primitive bladder |
Present |
|
2S
,
2A
|
Expression is present throughout the bladder.
|
TS20: urinary system |
Present |
Regionally restricted |
2S
,
2A
|
Expression is present in the urethra.
|
Specimen
3A:
embryonic day 14.5
(more )
Specimen
3A:
(close )
Genetic Background:
|
NMRI
|
Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Fresh Frozen
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: embryo |
Present |
|
3A
|
There is widespread expression throughout the embryo.
|
TS22: corpus striatum |
Strong |
|
3E
,
3A
|
|
TS22: neocortex |
Strong |
|
3E
,
3A
|
|
TS22: lateral ventricle choroid plexus |
Strong |
|
3A
,
3E
|
|
TS22: trigeminal ganglion |
Strong |
|
3A
|
|
TS22: adenohypophysis |
Strong |
|
3I
,
3A
|
Expression is present in Rathke's pouch.
|
TS22: diencephalon |
Strong |
Regionally restricted |
3I
,
3A
|
Expression is present in the diencephalon adjacent to Rathke's pouch.
|
TS22: medulla oblongata |
Strong |
|
3A
|
|
TS22: submandibular gland primordium |
Present |
|
3A
|
|
TS22: thymus primordium |
Present |
|
3M
,
3A
|
|
TS22: dorsal root ganglion |
Present |
|
3A
|
|
TS22: spinal cord |
Present |
|
3A
|
|
TS22: cartilage |
Present |
|
3A
|
Expression is present in the cartilage primordium.
|
TS22: lung |
Present |
|
3Q
,
3A
|
Expression is ubiquitous.
|
TS22: lobar bronchus |
Present |
|
3Q
,
3A
|
|
TS22: mesenchyme of metanephros |
Present |
|
3U
,
3A
|
Expression is present in the whole metanephron, including cortical, medullary, and mesenchymal regions.
|
TS22: metanephros |
Present |
|
3U
,
3A
|
Expression is present in the whole metanephron, including cortical, medullary, and mesenchymal regions.
|
TS22: renal cortex |
Present |
|
3U
,
3A
|
Expression is present in the whole metanephron, including cortical, medullary, and mesenchymal regions.
|
TS22: renal medulla |
Present |
|
3U
,
3A
|
Expression is present in the whole metanephron, including cortical, medullary, and mesenchymal regions.
|
TS22: heart |
Moderate |
|
3A
|
|
TS22: liver |
Moderate |
|
3A
,
3Q
|
|
Specimen
3C:
embryonic day 14.5
(more )
Specimen
3C:
(close )
Genetic Background:
|
NMRI
|
Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Fresh Frozen
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: embryo |
Present |
|
3C
|
There is widespread expression throughout the embryo.
|
TS22: olfactory epithelium |
Strong |
|
3K
,
3C
|
|
TS22: cerebellum |
Strong |
|
3G
,
3C
|
|
TS22: midbrain tegmentum |
Strong |
|
3G
,
3C
|
|
TS22: superior colliculus |
Strong |
|
3G
,
3C
|
|
TS22: medulla oblongata part of 4th ventricle choroid plexus |
Strong |
|
3G
,
3C
|
High expression levels are detected in the choroid plexus within the fourth ventricle.
|
TS22: metencephalon part of 4th ventricle choroid plexus |
Strong |
|
3G
,
3C
|
High expression levels are detected in the choroid plexus within the fourth ventricle.
|
TS22: adenohypophysis |
Strong |
|
3C
|
Expression is present in Rathke's pouch.
|
TS22: diencephalon |
Strong |
Regionally restricted |
3C
|
Expression is present in the diencephalon adjacent to Rathke's pouch.
|
TS22: medulla oblongata |
Strong |
|
3C
|
|
TS22: thymus primordium |
Present |
|
3C
|
|
TS22: intestine |
Present |
|
3S
,
3C
,
3W
|
Expression is present throughout all layers.
|
TS22: urogenital sinus |
Strong |
|
3S
,
3C
|
|
TS22: heart |
Moderate |
|
3C
,
3O
|
|
TS22: liver |
Moderate |
|
3C
|
|
Specimen
4A:
embryonic day 16.5
(more )
Specimen
4A:
(close )
Genetic Background:
|
NMRI
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Fresh Frozen
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: cerebral cortex |
Present |
|
4A
,
4E
|
|
TS24: neocortex |
Present |
Regionally restricted |
4E
,
4A
|
Expression is present in the ventricular zone of the neocortex.
|
TS24: corpus striatum |
Present |
|
4A
|
|
TS24: olfactory epithelium |
Present |
|
4A
,
4E
|
|
TS24: trigeminal ganglion |
Present |
|
4A
|
|
TS24: midbrain |
Present |
Regionally restricted |
4A
|
Expression is present in the tectum and the segmentum of the midbrain.
|
TS24: medulla oblongata |
Present |
|
4A
|
|
TS24: choroid plexus |
Weak |
|
4A
,
4E
|
|
TS24: adenohypophysis |
Absent |
|
4I
,
4A
|
Expression is no longer present in Rathke's pouch.
|
TS24: submandibular gland |
Strong |
|
4A
|
|
TS24: thymus |
Strong |
|
4A
|
|
TS24: lung |
Strong |
|
4A
,
4M
,
4U
|
Expression is present in all tissues.
|
TS24: bronchiole epithelium |
Trace |
|
4A
,
4U
|
Only marginal staining was observed in the epithelium of the main bronchus.
|
TS24: renal cortex |
Present |
|
4A
,
4Q
|
Expression is present in both cortical and medullary regions.
|
TS24: renal medulla |
Present |
|
4A
,
4Q
|
Expression is present in both cortical and medullary regions.
|
TS24: intestine epithelium |
Present |
|
4A
|
Expression is elevated in the epithelium at the base of the villi.
|
TS24: retina |
Present |
|
4Y1
,
4A
|
|
TS24: presumptive iris |
Present |
Regionally restricted |
4Y1
,
4A
|
Expression is present in the cuboidal epithelium lining the iris.
|
Specimen
4C:
embryonic day 16.5
(more )
Specimen
4C:
(close )
Genetic Background:
|
NMRI
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Fresh Frozen
|
Embedding:
|
Cryosection
|
Specimen
Table 1:
embryonic day 12.5
(more )
Specimen
Table 1:
(close )
Genetic Background:
|
NMRI
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Fresh Frozen
|
Embedding:
|
Cryosection
|
Specimen
Table 1:
embryonic day 14.5
(more )
Specimen
Table 1:
(close )
Genetic Background:
|
NMRI
|
Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Fresh Frozen
|
Embedding:
|
Cryosection
|
Specimen
Table 1:
embryonic day 16.5
(more )
Specimen
Table 1:
(close )
Genetic Background:
|
NMRI
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Fresh Frozen
|
Embedding:
|
Cryosection
|
|