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Tg(Nes-cre/ERT2)1Fsh
Transgene Detail
Summary
Symbol: Tg(Nes-cre/ERT2)1Fsh
Name: transgene insertion 1, Gordon Fishell
MGI ID: MGI:3774417
Synonyms: NestinCreERT2, Tg(Nes-cre/ESR1)1Fsh
Transgene: Tg(Nes-cre/ERT2)1Fsh  Location: unknown  
Alliance: Tg(Nes-cre/ERT2)1Fsh page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Nes-cre/ERT2)1Fsh expression driven by 1 gene
 
Mutation details: The intron 2 neural-specific enhancer from intron 2 was used to drive expression of an inducible cre/ESR1 (ET2) fusion in neural tissues. (J:130973)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Nes (species not specified)
Summary of all recombinase alleles driven by Nes.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Notes
Four lines were created and the one utilized exhibited an intermediate level of expression
References
Original:  J:130973 Balordi F, et al., Mosaic removal of hedgehog signaling in the adult SVZ reveals that the residual wild-type stem cells have a limited capacity for self-renewal. J Neurosci. 2007 Dec 26;27(52):14248-59
All:  30 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory