Tg(KLKB1-cre/ERT2)1Pcn Transgene Detail MGI Mouse (MGI:3775927)

Tg(KLKB1-cre/ERT2)1Pcn
Transgene Detail

Summary

Symbol:	Tg(KLKB1-cre/ERT2)1Pcn
Name:	transgene insertion 1, Pierre Chambon
MGI ID:	MGI:3775927
Synonyms:	PSA-Cre-ER^T2, Tg(KLK30-creESR1)1Pcn
Transgene:	Tg(KLKB1-cre/ERT2)1Pcn Location: unknown
Alliance:	Tg(KLKB1-cre/ERT2)1Pcn page

Transgene
origin

Strain of Origin:

Not Specified

Transgene
description

Transgene Type:

Transgenic (Inducible, Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Tg(KLKB1-cre/ERT2)1Pcn expression driven by 1 gene

The human KLKB1 was used to drive the expression of a cre/ERT2 cassette in the prostatic epithelium. (J:132170)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	KLKB1 (human) Summary of all recombinase alleles driven by KLKB1. Alliance human KLKB1 gene page

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Tumor Data

List all tumor models in MMHCdb carrying Tg(KLKB1-cre/ERT2)1Pcn

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

Original:	J:132170 Ratnacaram CK, et al., Temporally controlled ablation of PTEN in adult mouse prostate epithelium generates a model of invasive prostatic adenocarcinoma. Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2521-6
All:	8 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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