Flvcr1<tm1Jlab> Targeted Allele Detail MGI Mouse (MGI:3776021)

Flvcr1^tm1Jlab
Targeted Allele Detail

Summary

Symbol:	Flvcr1^tm1Jlab
Name:	feline leukemia virus subgroup C cellular receptor 1; targeted mutation 1, Janis L Abkowitz
MGI ID:	MGI:3776021
Synonyms:	Flvcr^flox
Gene:	Flvcr1 Location: Chr1:190738044-190758355 bp, - strand Genetic Position: Chr1, 96.28 cM
Alliance:	Flvcr1^tm1Jlab page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:132057
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S4/SvJae

Mutation
description

Allele Type:		Targeted (Conditional ready, No functional change)
Mutation:		Insertion
		Mutation details: A floxed neo cassette was inserted downstream of exon 1 and an additional loxP site was inserted upstream of exon 3. The neo cassette was removed by transient cre-mediated recombination to leave a floxed exon 3. (J:132057)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Disease models

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Flvcr1 Mutation:	32 strains or lines available

References

Original:	J:132057 Keel SB, et al., A heme export protein is required for red blood cell differentiation and iron homeostasis. Science. 2008 Feb 8;319(5864):825-8
All:	5 reference(s)

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