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Tg(Neurog1-cre/ERT2)1Good
Transgene Detail
Summary
Symbol: Tg(Neurog1-cre/ERT2)1Good
Name: transgene insertion 1, Lisa V Goodrich
MGI ID: MGI:3777275
Synonyms: Neurog1CreER, Ngn1CreER, Ngn1-CreERT2, Ngn-CreERT2, Tg(Neurog1-cre/ESR1)1Good
Transgene: Tg(Neurog1-cre/ERT2)1Good  Location: unknown  
Alliance: Tg(Neurog1-cre/ERT2)1Good page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Neurog1-cre/ERT2)1Good expression driven by 1 gene
 
Mutation details: A transgene was constructed where cre recombinase fused to the ligand-binding domain of a mutant human estrogen receptor was placed under the control of the upstream promoter and the downstream untranslated region of the Neurog1 gene. Cre activity was detected in cochlear ganglion neurons of transgenic mice when crossed with a cre-reporter strain and dosing with tamoxifen. (J:130813)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Neurog1 (species not specified)
Summary of all recombinase alleles driven by Neurog1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:130813 Koundakjian EJ, et al., Auditory neurons make stereotyped wiring decisions before maturation of their targets. J Neurosci. 2007 Dec 19;27(51):14078-88
All:  27 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
MGI 6.24 		The Jackson Laboratory