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Tg(Nes-cre/ERT2)1Jf
Transgene Detail
Summary
Symbol: Tg(Nes-cre/ERT2)1Jf
Name: transgene insertion 1, Jonas Frisen
MGI ID: MGI:3784516
Synonyms: Nestin-CreER, Nestin-Cre-ERT2, Tg(Nes-cre/ESR1)1Jf
Transgene: Tg(Nes-cre/ERT2)1Jf  Location: unknown  
Alliance: Tg(Nes-cre/ERT2)1Jf page
Transgene
origin
Strain of Origin:  CBA x C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Nes-cre/ERT2)1Jf expression driven by 1 gene
 
Mutation detailsThe enhancer from the second intron of rat Nestin in conjunction with the Hspa1b minimal promoter was used to drive neural stem and progenitor cell-specific expression of a cre/ESR1 (CRE-ERT2) fusion. Cre expression is tamoxifen-inducible. Eleven founder lines were created and one was analyzed (line numbers not specified). (J:133759)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Nes (rat)
Summary of all recombinase alleles driven by Nes.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:133759 Carlen M, et al., Genetic visualization of neurogenesis. Exp Cell Res. 2006 Sep 10;312(15):2851-9
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
08/02/2024
MGI 6.24
The Jackson Laboratory