Tg(Nes-cre/ERT2)1Jf
Transgene Detail
|
Symbol: |
Tg(Nes-cre/ERT2)1Jf |
Name: |
transgene insertion 1, Jonas Frisen |
MGI ID: |
MGI:3784516 |
Synonyms: |
Nestin-CreER, Nestin-Cre-ERT2, Tg(Nes-cre/ESR1)1Jf |
Transgene: |
Tg(Nes-cre/ERT2)1Jf Location: unknown
|
Alliance: |
Tg(Nes-cre/ERT2)1Jf page
|
|
Strain of Origin: |
CBA x C57BL/6
|
|
Transgene Type: |
|
Transgenic (Inducible, Recombinase) |
Inducer: |
|
tamoxifen |
Mutation: |
|
Insertion
|
|
|
Tg(Nes-cre/ERT2)1Jf expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Homolog in Mouse |
Note |
rat |
Nes (25491) |
|
|
|
|
|
Mutation details: The enhancer from the second intron of rat Nestin in conjunction with the Hspa1b minimal promoter was used to drive neural stem and progenitor cell-specific expression of a cre/ESR1 (CRE-ERT2) fusion. Cre expression is tamoxifen-inducible. Eleven founder lines were created and one was analyzed (line numbers not specified).
(J:133759)
|
|
|
Activity: |
Tissue activity of this recombinase allele
|
Driver:
|
Nes
(rat)
|
|
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
Original: |
J:133759 Carlen M, et al., Genetic visualization of neurogenesis. Exp Cell Res. 2006 Sep 10;312(15):2851-9 |
All: |
3 reference(s) |
|