Enpp1<asj> Chemically induced Allele Detail MGI Mouse (MGI:3785162)

Enpp1^asj
Chemically induced Allele Detail

Summary

Symbol:	Enpp1^asj
Name:	ectonucleotide pyrophosphatase/phosphodiesterase 1; ages with stiffened joints
MGI ID:	MGI:3785162
Gene:	Enpp1 Location: Chr10:24513812-24588057 bp, - strand Genetic Position: Chr10, 12.26 cM
Alliance:	Enpp1^asj page

Stiffening of the joints in Enpp1^asj/Enpp1^asj (right) mice, particularly in the forepaws

Show the 1 phenotype image(s) involving this allele.

Mutation
origin

Strain of Origin:

C57BL/6J

Mutation
description

Allele Type:		Chemically induced (ENU)
Mutation:		Single point mutation
		Mutation details: This ENU induced mutation was found to be an exon 7 T to A point mutation at position 737, predicted to change a valine to an aspartic acid. (J:174912)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Disease models

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Enpp1 Mutation:	11 strains or lines available

References

Original:	J:174912 Harris BS, et al., Ages with stiffened joints, A new mutation in Enpp1. MGI Direct Data Submission. 2011;
All:	21 reference(s)

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