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Enpp2tm1Vart
Targeted Allele Detail
Summary
Symbol: Enpp2tm1Vart
Name: ectonucleotide pyrophosphatase/phosphodiesterase 2; targeted mutation 1, Vassilis Aidinis
MGI ID: MGI:3785736
Synonyms: ATX floxed, Enpp2n
Gene: Enpp2  Location: Chr15:54702297-54816284 bp, - strand  Genetic Position: Chr15, 21.6 cM, cytoband D2
Alliance: Enpp2tm1Vart page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:134373
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details: A neomycin selection cassette has been inserted upstream of exon 1, and the neo cassette and exons 1 and 2 are flanked by loxP sites. Expression of Cre recombinase in mice bearing this allele results in excision of both exons and the selection cassette. (J:134373)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Enpp2 Mutation:  79 strains or lines available
References
Original:  J:134373 Aidinis V, Generation of mice bearing a floxed mutation of Enpp2 (ATX). MGI Direct Data Submission. 2008;
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory