Tg(Col1a2-cre/ERT,-ALPP)7Cpd Transgene Detail MGI Mouse (MGI:3785760)

Tg(Col1a2-cre/ERT,-ALPP)7Cpd
Transgene Detail

Summary

Symbol:	Tg(Col1a2-cre/ERT,-ALPP)7Cpd
Name:	transgene insertion 7, Christopher P Denton
MGI ID:	MGI:3785760
Synonyms:	Col1a2 Cre-ER, Col1a2-Cre-ER(T), Col1a2CreERT, Tg(Col1a2-cre/ERT)7Cpd, Tg(Col1a2-cre/ESR1)71Pcn, Tg(Col1a2-cre/ESR1)7Cpd
Transgene:	Tg(Col1a2-cre/ERT,-ALPP)7Cpd Location: unknown
Alliance:	Tg(Col1a2-cre/ERT,-ALPP)7Cpd page

Transgene
origin

Strain of Origin:

(C57BL/6 x DBA/2)F2

Transgene
description

Transgene Type:

Transgenic (Inducible, Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Tg(Col1a2-cre/ERT,-ALPP)7Cpd expression driven by 1 gene

Mutation details: The Col1a2 enhancer was used to drive fibroblast-specific expression of a cre/ERT fusion followed by an IRES-human placental alkaline-phosphatase reporter. Two lines were created (lines 7 and 8) and line 7 was used in subsequent analysis. (J:134447)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Col1a2 (species not specified) Summary of all recombinase alleles driven by Col1a2. Comparative matrix view of recombinase activities

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Disease models

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 4 strains available Cell Lines: 0 lines available

References

Original:	J:134447 Zheng B, et al., Ligand-dependent genetic recombination in fibroblasts : a potentially powerful technique for investigating gene function in fibrosis. Am J Pathol. 2002 May;160(5):1609-17
All:	107 reference(s)

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