Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Phenotypes | Disease models | Tumor data | Find Mice (IMSR) | References

Symbol:	Tlx3tm1(cre)Qima
Name:	T cell leukemia, homeobox 3; targeted mutation 1, Qiufu Ma
MGI ID:	MGI:3789185
Synonyms:	Rnx-Cre, Tlx3Cre
Gene:	Tlx3  Location: Chr11:33150752-33153589 bp, - strand  Genetic Position: Chr11, 19.21 cM, cytoband A5
Alliance:	Tlx3tm1(cre)Qima page

Germline Transmission:	Earliest citation of germline transmission: J:134327
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Tlx3tm1(cre)Qima expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Tlx3 (MGI:1351209)   Mutation details: A cre cassette followed by an frt-flanked neo was inserted into exon 2. Germ-line, flp-mediated recombination was used to remove the neo cassette. Cre expression recapitulates endogenous promoter activity. (J:134327)

Activity:	Tissue activity of this recombinase allele
Driver:	Tlx3 (mouse) Summary of all recombinase alleles driven by Tlx3. Alliance mouse Tlx3 gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

List all tumor models in MMHCdb carrying Tlx3tm1(cre)Qima

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tlx3 Mutation:	14 strains or lines available

Original:	J:134327 Xu Y, et al., Tlx1 and Tlx3 coordinate specification of dorsal horn pain-modulatory peptidergic neurons. J Neurosci. 2008 Apr 9;28(15):4037-46
All:	9 reference(s)