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Sema3ftm1Atai
Targeted Allele Detail
Summary
Symbol: Sema3ftm1Atai
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F; targeted mutation 1, Atsu Aiba
MGI ID: MGI:3790328
Synonyms: Sema3F(loxP)
Gene: Sema3f  Location: Chr9:107558699-107587674 bp, - strand  Genetic Position: Chr9, 58.91 cM, cytoband F2
Alliance: Sema3ftm1Atai page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:134616
Parent Cell Line:  EB3 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation details: A lacZ cassette was inserted into exon 3. Cre-mediated recombination removed the floxed selection cassette inserted downstream of exon 3. The absence of transcript expression was confirmed by northern blot and in situ hybridization. This was generated from Sema3ftm2Atai. (J:134616)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 12 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sema3f Mutation:  41 strains or lines available
Notes
ES cells = EB3, derived from E14TG2a. EB3 cells carry one allele of Pou5f1 that has been inactivated via targeted integration of E14TG2a ES cells with an IRESBSDpA selection cassette.
References
Original:  J:134616 Ito K, et al., Semaphorin 3F confines ventral tangential migration of lateral olfactory tract neurons onto the telencephalon surface. J Neurosci. 2008 Apr 23;28(17):4414-22
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory