Tg(CAG-flpe)16Ito
Transgene Detail
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| Symbol: |
Tg(CAG-flpe)16Ito |
| Name: |
transgene insertion 16, Shigeyoshi Itohara |
| MGI ID: |
MGI:3793304 |
| Synonyms: |
CAG-FLPe |
| Transgene: |
Tg(CAG-flpe)16Ito Location: unknown
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| Alliance: |
Tg(CAG-flpe)16Ito page
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(CAG-flpe)16Ito expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| chicken |
CAG |
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Mutation details: The CAG promoter (chicken beta-actin promoter with CMV enhancers) was used to drive expression of a FLPe gene with a nuclear localization signal. Five founder lines were established (lines 16, 32, 36, 37 and 41) with lines 16, 32 and 36 exhibiting 100% recombination when crossed to a mouse containing an frt-flanked allele; 10/11 mice of line 37 showed recombination. Mosaicism was noted in 2/9 of line 16 and in 1/8 of line 32 double transgenic mice. Line 16 was chosen as the representative line.
(J:108559)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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CAG
(chicken)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:108559 Kanki H, et al., High-efficiency CAG-FLPe deleter mice in C57BL/6J background. Exp Anim. 2006 Apr;55(2):137-41 |
| All: |
3 reference(s) |
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Analysis Tools
