Ppp1r1btm4Pggd
Targeted Allele Detail
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| Symbol: |
Ppp1r1btm4Pggd |
| Name: |
protein phosphatase 1, regulatory inhibitor subunit 1B; targeted mutation 4, Paul Greengard |
| MGI ID: |
MGI:3799291 |
| Synonyms: |
Ser97A-DARPP-32, Ser97-DARPP-32 |
| Gene: |
Ppp1r1b Location: Chr11:98239232-98248622 bp, + strand Genetic Position: Chr11, 61.75 cM
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| Alliance: |
Ppp1r1btm4Pggd page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:106270
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted |
| Mutation: |
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Nucleotide substitutions
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Serine 97 was replaced with an alanine to prevent phosphorylation. (J:107305)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Ppp1r1b Mutation: |
18 strains or lines available
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| Original: |
J:106270 Zhang Y, et al., Cocaine self-administration in mice is inversely related to phosphorylation at Thr34 (protein kinase A site) and Ser130 (kinase CK1 site) of DARPP-32. J Neurosci. 2006 Mar 8;26(10):2645-51 |
| All: |
3 reference(s) |
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Analysis Tools
