About   Help   FAQ
Nedd4Gt(XB786)Byg
Gene trapped Allele Detail
Summary
Symbol: Nedd4Gt(XB786)Byg
Name: neural precursor cell expressed, developmentally down-regulated 4; gene trap XB786, BayGenomics
MGI ID: MGI:3799317
Synonyms: Nedd4-1-trap
Gene: Nedd4  Location: Chr9:72569628-72657134 bp, + strand  Genetic Position: Chr9, 40.08 cM
Alliance: Nedd4Gt(XB786)Byg page
Mutation
origin
Mutant Cell Line:  XB786
Germline Transmission:  Earliest citation of germline transmission: J:137202
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT0pfs     Vector Type: gene trap
 
Mutation details: The gene trap vector, containing the lacZ gene, was inserted between exons 6 and 7. The absence of protein product was confirmed by western blot analysis on mouse embryonic fibroblast extracts. (J:137202)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nedd4 Mutation:  116 strains or lines available
Notes
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
References
Original:  J:137202 Fouladkou F, et al., The ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localization. Proc Natl Acad Sci U S A. 2008 Jun 24;105(25):8585-90
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory