Ccdc42<tm1(KOMP)Vlcg> Targeted Allele Detail MGI Mouse (MGI:3800251)

Ccdc42^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

Symbol:	Ccdc42^{tm1(KOMP)Vlcg}
Name:	coiled-coil domain containing 42; targeted mutation 1, Velocigene
MGI ID:	MGI:3800251
Synonyms:	Ccdc42^KO, Ccdc42^tm1Vlcg
Gene:	Ccdc42 Location: Chr11:68477863-68488777 bp, + strand Genetic Position: Chr11, 41.85 cM
Alliance:	Ccdc42^{tm1(KOMP)Vlcg} page
IMPC:	Ccdc42 gene page

Mutation
origin

Mutant Cell Lines:	10362A-D12, 10362A-F2, 10362B-D2
Germline Transmission:	Earliest citation of germline transmission: J:231668
Parent Cell Line:	VGB6 (ES Cell)
Strain of Origin:	C57BL/6NTac
Project Collection:	KOMP-Regeneron

Mutation
description

Allele Type:		Targeted (Null/knockout, Reporter)
Mutations:		Insertion, Intragenic deletion Vector: ZEN-Ub1
		Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 10697bp between positions 68400713-68411409 of Chromosome 11 (Genome Build37). All seven exons (i.e. the entire coding sequence of the gene) were replaced with a lacZ reporter and neomycin resistance cassette. (J:136110, J:231668)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 1 line available
Carrying any Ccdc42 Mutation:	23 strains or lines available

References

Original:	J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008;
All:	2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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