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Tg(HBB-cre)12Kpe
Transgene Detail
Summary
Symbol: Tg(HBB-cre)12Kpe
Name: transgene insertion 12, Kenneth Peterson
MGI ID: MGI:3800816
Synonyms: microLCR-betapr-Cre
Transgene: Tg(HBB-cre)12Kpe  Location: unknown  
Alliance: Tg(HBB-cre)12Kpe page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(HBB-cre)12Kpe expression driven by 1 gene
 
Mutation details: A transgenic construct containing the sequence encoding Cre recombinase under the control of the human beta hemoglobin (HBB) promoter, intron 2-enhancer fragment, and the human beta hemoglobin locus control region (LCR) was introduced into C57BL/6 donor eggs. Founder line 12 was established. Cre recombinase expression is detected in blood, brain, gonads, spleen and liver by RT-PCR analysis and in blood by RNAse protection assay. Recombination occurs at 50-100% efficiency in erythroid/megakarycytic cell lineages beginning at onset of hematopoiesis at approximately embryonic day 7.5. (J:89725, J:137519)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: HBB (human)
Summary of all recombinase alleles driven by HBB.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:137519 Peterson KR, Generation of an erythroid-specific cre transgenic mouse. MGI Direct Data Submission. 2008;
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory