Summary | Transgene origin | Transgene description | Recombinase activity | Phenotypes | Disease models | Tumor data | Find Mice (IMSR) | References

Symbol:	Tg(Wap-cre)51Nki
Name:	transgene insertion 51, The Netherlands Cancer Institute
MGI ID:	MGI:3801314
Synonyms:	Wcre
Transgene:	Tg(Wap-cre)51Nki  Location: unknown
Alliance:	Tg(Wap-cre)51Nki page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Wap-cre)51Nki expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Wap (MGI:98943)   Mutation details: The transgene consists of a 4.5 kb genomic fragment of the mouse whey acidic protein promoter (Wap) followed by a rabbit beta-globin intron, cre coding sequence, and a transcription termination/polyadenylation fragment from the human growth hormone gene. The purified 7.8 kb fragment was microinjected into one-cell stage embryos from FVB/N mice. This is a high expressing line (51). (J:171765)

Activity:	Tissue activity of this recombinase allele
Driver:	Wap (mouse) Summary of all recombinase alleles driven by Wap. Alliance mouse Wap gene page

View phenotypes and curated references for all genotypes (concatenated display).

List all tumor models in MMHCdb carrying Tg(Wap-cre)51Nki

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:171765 Derksen PW, et al., Mammary-specific inactivation of E-cadherin and p53 impairs functional gland development and leads to pleomorphic invasive lobular carcinoma in mice. Dis Model Mech. 2011 May-Jun;4(3):347-58
All:	14 reference(s)